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Is anastrozole hard on the liver? In clinical trials, anastrozole has generally shown a good liver safety profile [6]. Our patient, however, developed acute liver damage during treatment with this aromatase inhibitor, but achieved a prompt and full recovery after discontinuation of the drug.
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What does aromatase inhibitor do? Aromatase inhibitors work by blocking the enzyme aromatase, which turns the hormone androgen into small amounts of estrogen in the body. This means that less estrogen is available to stimulate the growth of hormone-receptor-positive breast cancer cells.
